Michel

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Réseau BIOTechno is an association which organizes professional forums dedicated to the career of young researchers in biotechnologies. For the 2019 edition of the forum I joined the board of organizers and was responsible for the program of the forum. During the organization, I contacted several companies to ask for their partnership, I managed a part of the team for contacting speakers and professionals that would give a talk or conduct workshop during the forum

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The team aim at developping new therapeutic approaches for myotonic dystrophy using muscle cell lines derived from patients and animal models. We also had a project in collaboration with a team from the Netherlands aiming at modifying cell lines using CRISPR-Cas9 technology. I was involved in multiples projects that I conduced in parallel. Notably, I cloned shRNA and cDNA of interest using the classical restriction – ligation cloning or other techniques, such as HiFi Cloning. After AAV production by a dedicated platform, I injected these viruses in mice and analysed their effects. I was co-responsible for monitoring the stock of consumables and reagents in the lab and was ordering some when needed. I was contacting companies for delivery, billing and products issues. I was part of the 'communication commission' of the center whose aim was to facilitate the internal scientific reflection and to promote the interaction between the teams. We organized Journal Clubs, Seminars and an annual retreat. I volunteer during the Covid-19 pandemic to help enter medical data in a registry under the supervision of the senior clinical research associate, allowing downstream analysis by a bio-informatician. International congress : Myology 2019 - About muscle physiology and neuromuscular disorders in general as well as gene therapy, pharmacogenomics, current clinical trials..

I stayed for 3 months in the team where I obtained my PhD, in order to finish the projects I was involved in and also to end the writing of a publication based on my thesis work (submitted and currently under review). Moreover we are now trying to patent a part of my results which could be of interest for a therapeutic approach (with the help of Conectus Alsace and an Intellectual Property Law Firm).